17-AAG increases autophagic removal of mutant androgen receptor in spinal and bulbar muscular atrophy. [electronic resource]
Producer: 20110927Description: 83-95 p. digitalISSN:- 1095-953X
- Animals
- Autophagy -- drug effects
- Benzoquinones -- pharmacology
- Cell Line, Transformed
- Lactams, Macrocyclic -- pharmacology
- Mice
- Motor Neurons -- drug effects
- Muscular Atrophy, Spinal -- drug therapy
- Mutation -- genetics
- Neuroprotective Agents -- pharmacology
- Proteostasis Deficiencies -- drug therapy
- Receptors, Androgen -- genetics
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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