17α-alkynyl 3α, 17β-androstanediol non-clinical and clinical pharmacology, pharmacokinetics and metabolism. [electronic resource]
Producer: 20120508Description: 59-78 p. digitalISSN:- 1573-0646
- Administration, Oral
- Androstanols -- administration & dosage
- Androstenedione -- blood
- Animals
- Antineoplastic Agents, Hormonal -- administration & dosage
- Biotransformation
- Cell Line, Tumor
- Chromatography, Liquid
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- biosynthesis
- Dehydroepiandrosterone -- blood
- Dogs
- Drug Administration Schedule
- Enzyme Induction
- Enzyme Inhibitors -- pharmacology
- Female
- Humans
- Macaca fascicularis
- Male
- Metabolomics
- Mice
- Microsomes, Liver -- drug effects
- Prostatic Neoplasms -- drug therapy
- Rats
- Rats, Sprague-Dawley
- Receptors, Cytoplasmic and Nuclear -- drug effects
- Species Specificity
- Tandem Mass Spectrometry
- Testosterone -- blood
- Transcriptional Activation -- drug effects
- Transfection
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Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Comparative Study; Journal Article; Multicenter Study
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