The complement component C5a is present in human coronary lesions in vivo and induces the expression of MMP-1 and MMP-9 in human macrophages in vitro. [electronic resource]
Producer: 20110308Description: 35-44 p. digitalISSN:- 1530-6860
- Cells, Cultured
- Complement C5a -- genetics
- Coronary Vessels -- metabolism
- Fluorescent Antibody Technique
- Gene Expression -- drug effects
- Humans
- Immunohistochemistry
- Macrophages -- drug effects
- Masoprocol -- pharmacology
- Matrix Metalloproteinase 1 -- genetics
- Matrix Metalloproteinase 9 -- genetics
- NF-kappa B -- antagonists & inhibitors
- Plaque, Atherosclerotic -- metabolism
- Quinazolines -- pharmacology
- RNA, Messenger -- genetics
- Receptor, Anaphylatoxin C5a -- metabolism
- Recombinant Proteins -- pharmacology
- Reverse Transcriptase Polymerase Chain Reaction
- Transcription Factor AP-1 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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