Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis. [electronic resource]
Producer: 20110208Description: 152-60 p. digitalISSN:- 1873-3913
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Benzoquinones -- pharmacology
- CCAAT-Enhancer-Binding Proteins -- metabolism
- Cell Cycle Proteins -- metabolism
- Cell Line
- Cyclic Nucleotide Phosphodiesterases, Type 1 -- antagonists & inhibitors
- DNA-Binding Proteins -- metabolism
- Down-Regulation
- Humans
- Isoenzymes -- genetics
- Jurkat Cells
- Nuclear Proteins -- metabolism
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- enzymology
- RNA Interference
- Tumor Protein p73
- Tumor Suppressor Proteins -- metabolism
- Ubiquitin-Protein Ligases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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