Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes. [electronic resource]
Producer: 20110125Description: 8488-98 p. digitalISSN:- 1520-4995
- Adaptor Proteins, Signal Transducing -- antagonists & inhibitors
- Amino Acid Sequence
- Carrier Proteins -- antagonists & inhibitors
- Cell Line
- Enzyme Inhibitors -- pharmacology
- Humans
- Intracellular Signaling Peptides and Proteins
- Kinetics
- Mechanistic Target of Rapamycin Complex 1
- Metals -- metabolism
- Molecular Sequence Data
- Multiprotein Complexes
- Phosphorylation
- Proteins -- antagonists & inhibitors
- Rapamycin-Insensitive Companion of mTOR Protein
- Recombinant Proteins -- antagonists & inhibitors
- Regulatory-Associated Protein of mTOR
- Sirolimus -- pharmacology
- Substrate Specificity
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Up-Regulation
- mTOR Associated Protein, LST8 Homolog
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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