Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes.

Tao, Zhihua

Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes. [electronic resource] - Biochemistry Oct 2010 - 8488-98 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4995

10.1021/bi100673c doi


Adaptor Proteins, Signal Transducing--antagonists & inhibitors
Amino Acid Sequence
Carrier Proteins--antagonists & inhibitors
Cell Line
Enzyme Inhibitors--pharmacology
Humans
Intracellular Signaling Peptides and Proteins
Kinetics
Mechanistic Target of Rapamycin Complex 1
Metals--metabolism
Molecular Sequence Data
Multiprotein Complexes
Phosphorylation
Proteins--antagonists & inhibitors
Rapamycin-Insensitive Companion of mTOR Protein
Recombinant Proteins--antagonists & inhibitors
Regulatory-Associated Protein of mTOR
Sirolimus--pharmacology
Substrate Specificity
TOR Serine-Threonine Kinases--antagonists & inhibitors
Up-Regulation
mTOR Associated Protein, LST8 Homolog