Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption. [electronic resource]
Producer: 20100820Description: 10169-76 p. digitalISSN:- 1529-2401
- Alanine -- genetics
- Alcohol Drinking -- drug therapy
- Analysis of Variance
- Animals
- Benzazepines -- therapeutic use
- Central Nervous System Depressants -- administration & dosage
- Disease Models, Animal
- Dopamine -- metabolism
- Dose-Response Relationship, Drug
- Drinking Behavior -- drug effects
- Drug Combinations
- Ethanol -- administration & dosage
- Gene Expression Regulation -- drug effects
- Leucine -- genetics
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation -- genetics
- Neurons -- drug effects
- Nicotinic Agonists -- therapeutic use
- Proto-Oncogene Proteins c-fos -- metabolism
- Quinoxalines -- therapeutic use
- Receptors, Nicotinic -- deficiency
- Tyrosine 3-Monooxygenase -- metabolism
- Varenicline
- Ventral Tegmental Area -- cytology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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