Structure-function correlation of G6, a novel small molecule inhibitor of Jak2: indispensability of the stilbenoid core. [electronic resource]
Producer: 20101104Description: 31399-407 p. digitalISSN:- 1083-351X
- Amino Acid Substitution
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Drug Screening Assays, Antitumor
- Humans
- Janus Kinase 2 -- antagonists & inhibitors
- Mutation, Missense
- Polycythemia Vera -- drug therapy
- Protein Kinase Inhibitors -- chemistry
- STAT3 Transcription Factor -- genetics
- STAT5 Transcription Factor -- genetics
- Stilbenes -- chemistry
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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