Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds. [electronic resource]
Producer: 20101230Description: 6934-52 p. digitalISSN:- 1464-3391
- Animals
- Binding Sites
- Computer Simulation
- Female
- Furans -- chemistry
- Humans
- Imidazoles -- chemistry
- Mice
- Mutation
- Protein Kinase Inhibitors -- chemical synthesis
- Protein Structure, Tertiary
- Proto-Oncogene Proteins B-raf -- antagonists & inhibitors
- Pyrazoles -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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