Type 1 diabetes in BioBreeding rats is critically linked to an imbalance between Th17 and regulatory T cells and an altered TCR repertoire. [electronic resource]
Producer: 20100922Description: 2285-94 p. digitalISSN:- 1550-6606
- Adoptive Transfer
- Animals
- Cell Line
- Diabetes Mellitus, Type 1 -- genetics
- Female
- Flow Cytometry
- GTP-Binding Proteins -- genetics
- Green Fluorescent Proteins -- genetics
- Humans
- Interleukin-17 -- immunology
- Interleukin-2 Receptor alpha Subunit -- immunology
- Lymphocyte Count
- Lymphopenia -- genetics
- Male
- Mutation
- Rats
- Rats, Inbred BB
- Rats, Transgenic
- Receptors, Antigen, T-Cell -- immunology
- T-Lymphocytes -- immunology
- T-Lymphocytes, Helper-Inducer -- immunology
- T-Lymphocytes, Regulatory -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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