Type 1 diabetes in BioBreeding rats is critically linked to an imbalance between Th17 and regulatory T cells and an altered TCR repertoire.
van den Brandt, Jens
Type 1 diabetes in BioBreeding rats is critically linked to an imbalance between Th17 and regulatory T cells and an altered TCR repertoire. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Aug 2010 - 2285-94 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1550-6606
10.4049/jimmunol.1000462 doi
Adoptive Transfer
Animals
Cell Line
Diabetes Mellitus, Type 1--genetics
Female
Flow Cytometry
GTP-Binding Proteins--genetics
Green Fluorescent Proteins--genetics
Humans
Interleukin-17--immunology
Interleukin-2 Receptor alpha Subunit--immunology
Lymphocyte Count
Lymphopenia--genetics
Male
Mutation
Rats
Rats, Inbred BB
Rats, Transgenic
Receptors, Antigen, T-Cell--immunology
T-Lymphocytes--immunology
T-Lymphocytes, Helper-Inducer--immunology
T-Lymphocytes, Regulatory--immunology
Type 1 diabetes in BioBreeding rats is critically linked to an imbalance between Th17 and regulatory T cells and an altered TCR repertoire. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Aug 2010 - 2285-94 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1550-6606
10.4049/jimmunol.1000462 doi
Adoptive Transfer
Animals
Cell Line
Diabetes Mellitus, Type 1--genetics
Female
Flow Cytometry
GTP-Binding Proteins--genetics
Green Fluorescent Proteins--genetics
Humans
Interleukin-17--immunology
Interleukin-2 Receptor alpha Subunit--immunology
Lymphocyte Count
Lymphopenia--genetics
Male
Mutation
Rats
Rats, Inbred BB
Rats, Transgenic
Receptors, Antigen, T-Cell--immunology
T-Lymphocytes--immunology
T-Lymphocytes, Helper-Inducer--immunology
T-Lymphocytes, Regulatory--immunology