A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal. [electronic resource]
Producer: 20101112Description: 186-97 p. digitalISSN:- 1875-9777
- Adaptor Proteins, Signal Transducing -- metabolism
- Animals
- Apoptosis -- radiation effects
- Apoptosis Regulatory Proteins -- metabolism
- Cell Lineage -- radiation effects
- Cell Proliferation -- radiation effects
- Cell Survival -- radiation effects
- Cytoprotection -- radiation effects
- DNA Breaks, Double-Stranded -- radiation effects
- DNA Damage
- HeLa Cells
- Hematopoietic Stem Cells -- cytology
- Humans
- Mice
- Myelopoiesis -- radiation effects
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Radiation, Ionizing
- Recombination, Genetic -- radiation effects
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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