Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines. [electronic resource]
Producer: 20101021Description: 114-23 p. digitalISSN:- 1521-0103
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- antagonists & inhibitors
- Arsenic Trioxide
- Arsenicals -- pharmacology
- Blotting, Western
- Cell Survival -- drug effects
- Curcumin -- pharmacology
- Electrophoretic Mobility Shift Assay
- Flow Cytometry
- Glutathione -- metabolism
- HL-60 Cells
- Humans
- Indazoles -- pharmacology
- Membrane Potentials -- drug effects
- Mitochondria -- drug effects
- Oxidants -- pharmacology
- Oxides -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Protein Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- biosynthesis
- Reactive Oxygen Species -- metabolism
- U937 Cells
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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