Dihydrotestosterone protects human vascular endothelial cells from H(2)O(2)-induced apoptosis through inhibition of caspase-3, caspase-9 and p38 MAPK. [electronic resource]
Producer: 20101228Description: 254-9 p. digitalISSN:- 1879-0712
- Androgens -- pharmacology
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Caspase 9 -- metabolism
- Caspases -- metabolism
- Cell Line
- Cell Survival -- drug effects
- Dihydrotestosterone -- pharmacology
- Down-Regulation -- drug effects
- Endothelium, Vascular -- drug effects
- Humans
- Hydrogen Peroxide -- toxicity
- Mitochondria -- drug effects
- Osmolar Concentration
- Oxidants -- toxicity
- Oxidative Stress -- drug effects
- Phosphorylation -- drug effects
- Plaque, Atherosclerotic -- prevention & control
- Protective Agents -- pharmacology
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article
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