MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation. [electronic resource]
Producer: 20110505Description: 405-17 p. digitalISSN:- 1573-7373
- Adult
- Astrocytoma -- genetics
- Brain Neoplasms -- genetics
- DNA Methylation
- DNA Modification Methylases -- genetics
- DNA Repair Enzymes -- genetics
- Disease Progression
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Male
- Middle Aged
- Mutation -- genetics
- Prognosis
- Promoter Regions, Genetic -- genetics
- Tumor Suppressor Protein p53 -- genetics
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article
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