Efficient overcoming of drug resistance to anticancer nucleoside analogs by nanodelivery of active phosphorylated drugs. [electronic resource]
Producer: 20101015Description: 281-9 p. digitalISSN:- 1873-3476
- Animals
- Antimetabolites, Antineoplastic -- chemistry
- Apoptosis -- drug effects
- Biological Transport
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Chemistry, Pharmaceutical
- Cytarabine -- chemistry
- Deoxycytidine -- analogs & derivatives
- Dose-Response Relationship, Drug
- Drug Carriers
- Drug Resistance
- Drug Resistance, Neoplasm
- Gels
- Humans
- Inhibitory Concentration 50
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Nanoparticles
- Nanotechnology
- Phosphorylation
- Protein Tyrosine Phosphatase, Non-Receptor Type 22 -- metabolism
- Technology, Pharmaceutical -- methods
- Time Factors
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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