IL-2-deprivation and TGF-beta are two non-redundant suppressor mechanisms of CD4+CD25+ regulatory T cell which jointly restrain CD4+CD25- cell activation. [electronic resource]
Producer: 20101103Description: 61-8 p. digitalISSN:- 1879-0542
- Animals
- CD24 Antigen -- metabolism
- Cells, Cultured
- Humans
- Immune Tolerance
- Interleukin-2 -- genetics
- Interleukin-2 Receptor alpha Subunit -- metabolism
- Lymphocyte Activation -- drug effects
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Knockout
- T-Lymphocytes, Regulatory -- drug effects
- Transforming Growth Factor beta -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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