IL-2-deprivation and TGF-beta are two non-redundant suppressor mechanisms of CD4+CD25+ regulatory T cell which jointly restrain CD4+CD25- cell activation.

Wang, Guohua

IL-2-deprivation and TGF-beta are two non-redundant suppressor mechanisms of CD4+CD25+ regulatory T cell which jointly restrain CD4+CD25- cell activation. [electronic resource] - Immunology letters Aug 2010 - 61-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1879-0542

10.1016/j.imlet.2010.06.001 doi


Animals
CD24 Antigen--metabolism
Cells, Cultured
Humans
Immune Tolerance
Interleukin-2--genetics
Interleukin-2 Receptor alpha Subunit--metabolism
Lymphocyte Activation--drug effects
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
T-Lymphocytes, Regulatory--drug effects
Transforming Growth Factor beta--immunology