ARQ 197, a novel and selective inhibitor of the human c-Met receptor tyrosine kinase with antitumor activity. [electronic resource]
Producer: 20100916Description: 1544-53 p. digitalISSN:- 1538-8514
- Animals
- Apoptosis -- drug effects
- Caspases -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Humans
- Immunosuppression Therapy
- Mice
- Mice, Nude
- Neoplasms -- enzymology
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- chemistry
- Proto-Oncogene Mas
- Proto-Oncogene Proteins c-met -- antagonists & inhibitors
- Pyrroles -- chemistry
- Pyrrolidinones -- chemistry
- Quinolines -- chemistry
- Signal Transduction -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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