Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A. [electronic resource]
Producer: 20100712Description: 1407-14 p. digitalISSN:- 1524-4636
- Adamantane -- analogs & derivatives
- Animals
- Cells, Cultured
- Cellular Senescence -- drug effects
- Cyclic AMP -- metabolism
- Cyclic AMP Response Element-Binding Protein -- metabolism
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- DNA Damage
- Diabetes Mellitus -- drug therapy
- Dipeptidyl-Peptidase IV Inhibitors -- pharmacology
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Endothelial Cells -- drug effects
- Enzyme Activation
- Exenatide
- Glucagon-Like Peptide 1 -- metabolism
- Glucagon-Like Peptide-1 Receptor
- Heme Oxygenase-1 -- metabolism
- Humans
- Hydrogen Peroxide -- pharmacology
- Hypoglycemic Agents -- pharmacology
- Male
- NAD(P)H Dehydrogenase (Quinone) -- metabolism
- Nitriles -- pharmacology
- Oxidants -- pharmacology
- Oxidative Stress -- drug effects
- Peptides -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Pyrrolidines -- pharmacology
- Rats
- Rats, Zucker
- Reactive Oxygen Species -- metabolism
- Receptors, Glucagon -- metabolism
- Signal Transduction
- Venoms -- pharmacology
- Vildagliptin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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