The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma. [electronic resource]
Producer: 20100608Description: 1031-44 p. digitalISSN:- 1540-9538
- Animals
- Antigens, CD -- genetics
- Antigens, Differentiation, T-Lymphocyte -- genetics
- Chromosomes, Human, Pair 5 -- genetics
- Chromosomes, Human, Pair 9 -- genetics
- Disease Models, Animal
- Embryonic Stem Cells -- physiology
- Gene Expression Regulation, Neoplastic
- Humans
- Interleukin-2 -- genetics
- Intracellular Signaling Peptides and Proteins -- genetics
- Lectins, C-Type -- genetics
- Lymphoma, T-Cell, Peripheral -- genetics
- Lymphoproliferative Disorders -- genetics
- Mice
- Protein-Tyrosine Kinases -- genetics
- Receptors, Antigen, T-Cell -- genetics
- Recombinant Fusion Proteins -- metabolism
- Signal Transduction
- Spleen -- enzymology
- Syk Kinase
- Translocation, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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