Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism. [electronic resource]
Producer: 20100528Description: 1371-7 p. digitalISSN:- 1532-1827
- Aged
- Alanine Transaminase -- metabolism
- Antineoplastic Agents -- adverse effects
- Bilirubin -- metabolism
- Carcinoma, Renal Cell -- drug therapy
- Clinical Trials, Phase II as Topic
- Clinical Trials, Phase III as Topic
- Female
- Genotype
- Gilbert Disease -- genetics
- Glucuronosyltransferase -- antagonists & inhibitors
- Humans
- Hyperbilirubinemia -- chemically induced
- Indazoles
- Kidney Neoplasms -- drug therapy
- Liver -- enzymology
- Male
- Middle Aged
- Nephrectomy
- Polymorphism, Genetic
- Pyrimidines -- adverse effects
- Sulfonamides -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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