Influences of thiopurine methyltransferase genotype and activity on thiopurine-induced leukopenia in Korean patients with inflammatory bowel disease: a retrospective cohort study. [electronic resource]
Producer: 20110201Description: e242-8 p. digitalISSN:- 1539-2031
- Academic Medical Centers
- Adolescent
- Adult
- Anti-Inflammatory Agents -- adverse effects
- Asian People -- genetics
- Chi-Square Distribution
- Chromatography, High Pressure Liquid
- Female
- Gastrointestinal Agents -- adverse effects
- Genetic Predisposition to Disease
- Heterozygote
- Homozygote
- Humans
- Inflammatory Bowel Diseases -- drug therapy
- Kaplan-Meier Estimate
- Leukopenia -- chemically induced
- Male
- Mercaptopurine -- adverse effects
- Methyltransferases -- genetics
- Phenotype
- Proportional Hazards Models
- Pyrophosphatases -- genetics
- Republic of Korea
- Retrospective Studies
- Risk Assessment
- Risk Factors
- Tandem Mass Spectrometry
- Treatment Outcome
- Young Adult
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Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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