Influences of thiopurine methyltransferase genotype and activity on thiopurine-induced leukopenia in Korean patients with inflammatory bowel disease: a retrospective cohort study.

Kim, Jae Hak

Influences of thiopurine methyltransferase genotype and activity on thiopurine-induced leukopenia in Korean patients with inflammatory bowel disease: a retrospective cohort study. [electronic resource] - Journal of clinical gastroenterology - e242-8 p. digital

Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

1539-2031

10.1097/MCG.0b013e3181d6baf5 doi


Academic Medical Centers
Adolescent
Adult
Anti-Inflammatory Agents--adverse effects
Asian People--genetics
Chi-Square Distribution
Chromatography, High Pressure Liquid
Female
Gastrointestinal Agents--adverse effects
Genetic Predisposition to Disease
Heterozygote
Homozygote
Humans
Inflammatory Bowel Diseases--drug therapy
Kaplan-Meier Estimate
Leukopenia--chemically induced
Male
Mercaptopurine--adverse effects
Methyltransferases--genetics
Phenotype
Proportional Hazards Models
Pyrophosphatases--genetics
Republic of Korea
Retrospective Studies
Risk Assessment
Risk Factors
Tandem Mass Spectrometry
Treatment Outcome
Young Adult