Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis. [electronic resource]
Producer: 20100712Description: 353-62 p. digitalISSN:- 1557-3125
- Animals
- CDC2-CDC28 Kinases
- Carrier Proteins -- genetics
- Cell Proliferation
- Cell Transformation, Neoplastic -- genetics
- Cells, Cultured
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclin-Dependent Kinases -- genetics
- Gene Expression Regulation, Neoplastic -- genetics
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Lymphoma, B-Cell -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Proto-Oncogene Proteins c-myc -- genetics
- S-Phase Kinase-Associated Proteins -- genetics
- Tumor Cells, Cultured
- Tumor Suppressor Proteins -- genetics
- Up-Regulation -- physiology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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