Atorvastatin induces apoptosis in vitro and slows growth of tumor xenografts but not polyp formation in MIN mice. [electronic resource]
Producer: 20101116Description: 3086-94 p. digitalISSN:- 1573-2568
- Animals
- Apoptosis -- drug effects
- Atorvastatin
- Colonic Neoplasms -- prevention & control
- Colonic Polyps -- prevention & control
- DNA Fragmentation
- Disease Models, Animal
- Heptanoic Acids -- pharmacology
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Immunoblotting
- In Situ Nick-End Labeling
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Mice, Nude
- Pyrroles -- pharmacology
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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