Atorvastatin induces apoptosis in vitro and slows growth of tumor xenografts but not polyp formation in MIN mice.
Huang, Emina H
Atorvastatin induces apoptosis in vitro and slows growth of tumor xenografts but not polyp formation in MIN mice. [electronic resource] - Digestive diseases and sciences Nov 2010 - 3086-94 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1573-2568
10.1007/s10620-010-1157-x doi
Animals
Apoptosis--drug effects
Atorvastatin
Colonic Neoplasms--prevention & control
Colonic Polyps--prevention & control
DNA Fragmentation
Disease Models, Animal
Heptanoic Acids--pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Immunoblotting
In Situ Nick-End Labeling
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Nude
Pyrroles--pharmacology
Tumor Cells, Cultured
Xenograft Model Antitumor Assays
Atorvastatin induces apoptosis in vitro and slows growth of tumor xenografts but not polyp formation in MIN mice. [electronic resource] - Digestive diseases and sciences Nov 2010 - 3086-94 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1573-2568
10.1007/s10620-010-1157-x doi
Animals
Apoptosis--drug effects
Atorvastatin
Colonic Neoplasms--prevention & control
Colonic Polyps--prevention & control
DNA Fragmentation
Disease Models, Animal
Heptanoic Acids--pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Immunoblotting
In Situ Nick-End Labeling
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Nude
Pyrroles--pharmacology
Tumor Cells, Cultured
Xenograft Model Antitumor Assays