Mechanistic characterization and molecular modeling of hepatitis B virus polymerase resistance to entecavir. [electronic resource]
Producer: 20100930Description: e9195 p. digitalISSN:- 1932-6203
- Amino Acid Sequence
- Amino Acid Substitution
- Antiviral Agents -- pharmacology
- Binding Sites -- genetics
- Drug Resistance, Viral -- genetics
- Guanine -- analogs & derivatives
- Guanosine Triphosphate -- chemistry
- Hep G2 Cells
- Hepatitis B virus -- enzymology
- Humans
- Hydrogen Bonding
- Kinetics
- Lamivudine -- pharmacology
- Models, Molecular
- Protein Binding
- Protein Structure, Tertiary
- RNA-Directed DNA Polymerase -- chemistry
- Substrate Specificity
- Viral Proteins -- chemistry
- Virus Replication -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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