Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice. [electronic resource]
Producer: 20100319Description: 2611-22 p. digitalISSN:- 1529-2401
- 6-Cyano-7-nitroquinoxaline-2,3-dione -- pharmacology
- Animals
- Anti-Anxiety Agents -- pharmacology
- Bicuculline -- pharmacology
- Cerebral Cortex -- cytology
- Cyclic Nucleotide-Gated Cation Channels -- antagonists & inhibitors
- Desoxycorticosterone -- analogs & derivatives
- Excitatory Amino Acid Antagonists -- pharmacology
- Excitatory Postsynaptic Potentials -- drug effects
- Female
- GABA Agents -- pharmacology
- Homeostasis -- genetics
- Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
- Male
- Membrane Potentials -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Models, Neurological
- Patch-Clamp Techniques -- methods
- Potassium Channels -- deficiency
- Protein Subunits -- genetics
- Pyramidal Cells -- physiology
- Pyridazines -- pharmacology
- Pyrimidines -- pharmacology
- Receptors, GABA-A -- physiology
- Sodium Channel Blockers -- pharmacology
- Synapses -- physiology
- Tetrodotoxin -- pharmacology
- Up-Regulation -- drug effects
- Valine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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