AC480, formerly BMS-599626, a pan Her inhibitor, enhances radiosensitivity and radioresponse of head and neck squamous cell carcinoma cells in vitro and in vivo. [electronic resource]
Producer: 20110916Description: 554-61 p. digitalISSN:- 1573-0646
- Animals
- Apoptosis -- drug effects
- Blotting, Western
- Carbamates -- pharmacology
- Carcinoma, Squamous Cell -- drug therapy
- Cell Count
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- ErbB Receptors -- metabolism
- Head and Neck Neoplasms -- drug therapy
- Histones -- metabolism
- Humans
- Immunoprecipitation
- Male
- Mice
- Mice, Nude
- Radiation Tolerance -- drug effects
- Radiation, Ionizing
- Receptor, ErbB-2 -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Triazines -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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