Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor. [electronic resource]
Producer: 20100504Description: 2346-56 p. digitalISSN:- 1476-5594
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Drug Resistance, Neoplasm
- ErbB Receptors -- antagonists & inhibitors
- Gefitinib
- Gene Amplification
- Humans
- Lung Neoplasms -- drug therapy
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Quinazolines -- pharmacology
- Quinazolinones -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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