Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis. [electronic resource]
Producer: 20100415Description: 7964-76 p. digitalISSN:- 1083-351X
- Alkaline Ceramidase -- genetics
- Apoptosis -- physiology
- Carcinoma, Squamous Cell -- pathology
- Cell Division -- physiology
- Ceramidases -- genetics
- Ceramides -- metabolism
- Culture Media, Serum-Free -- pharmacology
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Down-Regulation -- physiology
- Endothelial Cells -- cytology
- Gene Expression Regulation, Enzymologic
- HeLa Cells
- Humans
- Hydrolysis
- Keratinocytes -- cytology
- Muscle, Smooth, Vascular -- cytology
- RNA, Messenger -- metabolism
- RNA, Small Interfering
- Skin Neoplasms -- pathology
- Substrate Specificity
- Umbilical Veins -- cytology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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