Antifibrotic effect of Pirfenidone on orbital fibroblasts of patients with thyroid-associated ophthalmopathy by decreasing TIMP-1 and collagen levels. [electronic resource]
Producer: 20100611Description: 3061-6 p. digitalISSN:- 1552-5783
- Adult
- Aged
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Blotting, Western
- Cell Culture Techniques
- Cell Survival
- Collagen -- metabolism
- Dexamethasone -- pharmacology
- Dose-Response Relationship, Drug
- Enzyme-Linked Immunosorbent Assay
- Female
- Fibroblasts -- drug effects
- Graves Ophthalmopathy -- metabolism
- Humans
- Hydroxyproline -- metabolism
- Intercellular Signaling Peptides and Proteins -- pharmacology
- Interleukin-1beta -- pharmacology
- Male
- Middle Aged
- Orbit -- drug effects
- Pyridones -- pharmacology
- Tissue Inhibitor of Metalloproteinase-1 -- metabolism
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- Young Adult
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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