Corchorusin-D, a saikosaponin-like compound isolated from Corchorus acutangulus Lam., targets mitochondrial apoptotic pathways in leukemic cell lines (HL-60 and U937). [electronic resource]
Producer: 20100803Description: 709-19 p. digitalISSN:- 1432-0843
- Antineoplastic Agents, Phytogenic -- chemistry
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- genetics
- Blotting, Western
- Caspases -- metabolism
- Cell Nucleus -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Corchorus -- chemistry
- DNA Fragmentation -- drug effects
- Flow Cytometry
- Glycosides -- chemistry
- HL-60 Cells
- Humans
- Leukemia -- drug therapy
- Membrane Potentials -- drug effects
- Methanol
- Microscopy, Confocal
- Mitochondria -- drug effects
- Mitochondrial Membranes -- drug effects
- Plant Extracts -- pharmacology
- Poly Adenosine Diphosphate Ribose -- metabolism
- Signal Transduction -- drug effects
- Triterpenes -- chemistry
- U937 Cells
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Publication Type: Journal Article
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