Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells. [electronic resource]
Producer: 20100414Description: 419-26 p. digitalISSN:- 1460-2180
- Acetophenones -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Benzopyrans -- pharmacology
- Camptothecin -- analogs & derivatives
- Carcinoma -- metabolism
- Caspase 3 -- metabolism
- Cell Line, Tumor -- drug effects
- Cysteine Proteinase Inhibitors -- pharmacology
- Down-Regulation
- Enzyme Activation
- Female
- Humans
- Leukemia, Myeloid -- metabolism
- Male
- Neoplasm Proteins -- genetics
- Neoplasms -- metabolism
- Nuclear Proteins -- antagonists & inhibitors
- RNA Interference
- RNA, Small Interfering -- pharmacology
- Recombinant Fusion Proteins -- metabolism
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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