Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells.

Shen, Shao-Ming

Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells. [electronic resource] - Carcinogenesis Mar 2010 - 419-26 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2180

10.1093/carcin/bgp320 doi


Acetophenones--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Benzopyrans--pharmacology
Camptothecin--analogs & derivatives
Carcinoma--metabolism
Caspase 3--metabolism
Cell Line, Tumor--drug effects
Cysteine Proteinase Inhibitors--pharmacology
Down-Regulation
Enzyme Activation
Female
Humans
Leukemia, Myeloid--metabolism
Male
Neoplasm Proteins--genetics
Neoplasms--metabolism
Nuclear Proteins--antagonists & inhibitors
RNA Interference
RNA, Small Interfering--pharmacology
Recombinant Fusion Proteins--metabolism
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Substrate Specificity