Dexamethasone protects human fibroblasts from apoptosis via an S1P3-receptor subtype dependent activation of PKB/Akt and Bcl XL. [electronic resource]
Producer: 20100705Description: 449-59 p. digitalISSN:- 1096-1186
- Apoptosis -- drug effects
- Blotting, Western
- Caspase 3 -- metabolism
- Caspase 7 -- metabolism
- Cells, Cultured
- Dexamethasone -- pharmacology
- Fibroblasts -- drug effects
- Humans
- Membrane Potentials -- drug effects
- Mitochondrial Membranes -- drug effects
- Oncogene Protein v-akt -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Protective Agents
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA Interference
- Receptors, Lysosphingolipid -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Tumor Necrosis Factor-alpha -- metabolism
- bcl-X Protein -- metabolism
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Publication Type: Journal Article
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