Posttranslational modification of ataxin-7 at lysine 257 prevents autophagy-mediated turnover of an N-terminal caspase-7 cleavage fragment. [electronic resource]
Producer: 20091222Description: 15134-44 p. digitalISSN:- 1529-2401
- Acetylation
- Animals
- Animals, Newborn
- Ataxin-7
- Autophagy -- genetics
- Caspase 7 -- genetics
- Cells, Cultured
- Cerebellum -- cytology
- Disease Models, Animal
- Histone Deacetylases -- genetics
- Humans
- Lysosomal-Associated Membrane Protein 2 -- metabolism
- Mice
- Mice, Transgenic
- Mucoproteins -- genetics
- Nerve Tissue Proteins -- genetics
- Neurons -- physiology
- Peptides -- genetics
- Prions -- genetics
- Protein Processing, Post-Translational -- genetics
- Protein Subunits -- genetics
- RNA Interference -- physiology
- Spinocerebellar Ataxias -- genetics
- Transfection -- methods
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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