Cadmium-induced DNA damage triggers G(2)/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells. [electronic resource]
Producer: 20100309Description: F255-65 p. digitalISSN:- 1522-1466
- Animals
- Ataxia Telangiectasia Mutated Proteins
- Cadmium -- pharmacology
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- metabolism
- Cell Death
- Cell Division -- drug effects
- Cells, Cultured
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- Cyclin B -- metabolism
- DNA Damage
- DNA-Binding Proteins -- metabolism
- G2 Phase -- drug effects
- Kidney Tubules, Proximal -- cytology
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Protein Kinases -- drug effects
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Rats
- Reactive Oxygen Species -- metabolism
- Signal Transduction
- Staurosporine -- analogs & derivatives
- Tumor Suppressor Protein p53 -- deficiency
- Tumor Suppressor Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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