Potent new small-molecule inhibitor of botulinum neurotoxin serotype A endopeptidase developed by synthesis-based computer-aided molecular design. [electronic resource]
Producer: 20100426Description: e7730 p. digitalISSN:- 1932-6203
- Botulinum Toxins, Type A -- chemistry
- Botulism -- therapy
- Computational Biology -- methods
- Computer Simulation
- Drug Design
- Endopeptidases -- chemistry
- Humans
- Inhibitory Concentration 50
- Kinetics
- Magnetic Resonance Spectroscopy
- Molecular Conformation
- Molecular Dynamics Simulation
- Molecular Structure
- Software
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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