Potent new small-molecule inhibitor of botulinum neurotoxin serotype A endopeptidase developed by synthesis-based computer-aided molecular design.
Pang, Yuan-Ping
Potent new small-molecule inhibitor of botulinum neurotoxin serotype A endopeptidase developed by synthesis-based computer-aided molecular design. [electronic resource] - PloS one Nov 2009 - e7730 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1932-6203
10.1371/journal.pone.0007730 doi
Botulinum Toxins, Type A--chemistry
Botulism--therapy
Computational Biology--methods
Computer Simulation
Drug Design
Endopeptidases--chemistry
Humans
Inhibitory Concentration 50
Kinetics
Magnetic Resonance Spectroscopy
Molecular Conformation
Molecular Dynamics Simulation
Molecular Structure
Software
Structure-Activity Relationship
Potent new small-molecule inhibitor of botulinum neurotoxin serotype A endopeptidase developed by synthesis-based computer-aided molecular design. [electronic resource] - PloS one Nov 2009 - e7730 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1932-6203
10.1371/journal.pone.0007730 doi
Botulinum Toxins, Type A--chemistry
Botulism--therapy
Computational Biology--methods
Computer Simulation
Drug Design
Endopeptidases--chemistry
Humans
Inhibitory Concentration 50
Kinetics
Magnetic Resonance Spectroscopy
Molecular Conformation
Molecular Dynamics Simulation
Molecular Structure
Software
Structure-Activity Relationship