Procaine and procainamide inhibit the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells. [electronic resource]
Producer: 20100217Description: 1479-84 p. digitalISSN:- 1791-2431
- Adaptor Proteins, Signal Transducing -- genetics
- Anesthetics, Local -- pharmacology
- Anti-Arrhythmia Agents -- pharmacology
- Cell Line, Tumor
- Cell Proliferation
- DNA Methylation
- Dose-Response Relationship, Drug
- Gene Expression Regulation, Neoplastic
- Gene Silencing
- Humans
- Lung Neoplasms -- genetics
- Procainamide -- pharmacology
- Procaine -- pharmacology
- Promoter Regions, Genetic
- Repressor Proteins -- genetics
- Wnt Proteins -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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