Procaine and procainamide inhibit the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells.

Gao, Zhi

Procaine and procainamide inhibit the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells. [electronic resource] - Oncology reports Dec 2009 - 1479-84 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1791-2431

10.3892/or_00000590 doi


Adaptor Proteins, Signal Transducing--genetics
Anesthetics, Local--pharmacology
Anti-Arrhythmia Agents--pharmacology
Cell Line, Tumor
Cell Proliferation
DNA Methylation
Dose-Response Relationship, Drug
Gene Expression Regulation, Neoplastic
Gene Silencing
Humans
Lung Neoplasms--genetics
Procainamide--pharmacology
Procaine--pharmacology
Promoter Regions, Genetic
Repressor Proteins--genetics
Wnt Proteins--antagonists & inhibitors