Zoledronic acid delays wound healing of the tooth extraction socket, inhibits oral epithelial cell migration, and promotes proliferation and adhesion to hydroxyapatite of oral bacteria, without causing osteonecrosis of the jaw, in mice. [electronic resource]
Producer: 20100520Description: 165-75 p. digitalISSN:- 1435-5604
- Animals
- Bacterial Adhesion -- drug effects
- Bacterial Physiological Phenomena -- drug effects
- Bone Density Conservation Agents -- administration & dosage
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cells, Cultured
- Dental Plaque -- microbiology
- Diphosphonates -- administration & dosage
- Dose-Response Relationship, Drug
- Female
- Humans
- Imidazoles -- administration & dosage
- Jaw Diseases -- physiopathology
- Male
- Mice
- Mice, Inbred Strains
- Mouth Mucosa -- drug effects
- Neovascularization, Physiologic -- drug effects
- Osteogenesis -- drug effects
- Osteonecrosis -- physiopathology
- Streptococcus mutans -- drug effects
- Tooth Extraction
- Tooth Socket -- pathology
- Wound Healing -- drug effects
- Zoledronic Acid
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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