Curcumin inhibits srebp-2 expression in activated hepatic stellate cells in vitro by reducing the activity of specificity protein-1. [electronic resource]
Producer: 20100119Description: 5384-94 p. digitalISSN:- 1945-7170
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Binding Sites -- genetics
- Blotting, Western
- Cells, Cultured
- Chromatin Immunoprecipitation
- Curcumin -- pharmacology
- Dose-Response Relationship, Drug
- Electrophoretic Mobility Shift Assay
- Gene Expression -- drug effects
- Hepatic Stellate Cells -- cytology
- Luciferases -- genetics
- Mice
- Mice, Inbred C57BL
- PPAR gamma -- genetics
- Promoter Regions, Genetic -- genetics
- Protein Binding
- Rats
- Rats, Sprague-Dawley
- Reverse Transcriptase Polymerase Chain Reaction
- Sp1 Transcription Factor -- genetics
- Sterol Regulatory Element Binding Protein 2 -- genetics
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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