Curcumin inhibits srebp-2 expression in activated hepatic stellate cells in vitro by reducing the activity of specificity protein-1.

Kang, Qiaohua

Curcumin inhibits srebp-2 expression in activated hepatic stellate cells in vitro by reducing the activity of specificity protein-1. [electronic resource] - Endocrinology Dec 2009 - 5384-94 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1945-7170

10.1210/en.2009-0517 doi


Animals
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Binding Sites--genetics
Blotting, Western
Cells, Cultured
Chromatin Immunoprecipitation
Curcumin--pharmacology
Dose-Response Relationship, Drug
Electrophoretic Mobility Shift Assay
Gene Expression--drug effects
Hepatic Stellate Cells--cytology
Luciferases--genetics
Mice
Mice, Inbred C57BL
PPAR gamma--genetics
Promoter Regions, Genetic--genetics
Protein Binding
Rats
Rats, Sprague-Dawley
Reverse Transcriptase Polymerase Chain Reaction
Sp1 Transcription Factor--genetics
Sterol Regulatory Element Binding Protein 2--genetics
Transfection