beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt. [electronic resource]
Producer: 20091211Description: 6192-205 p. digitalISSN:- 1098-5549
- Casein Kinase I -- metabolism
- Cell Line
- Down-Regulation
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Humans
- Mutation
- Nuclear Proteins -- genetics
- Phosphoprotein Phosphatases
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA, Small Interfering -- genetics
- Ubiquitination
- beta-Transducin Repeat-Containing Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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