beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt.

Li, Xin

beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt. [electronic resource] - Molecular and cellular biology Dec 2009 - 6192-205 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1098-5549

10.1128/MCB.00681-09 doi


Casein Kinase I--metabolism
Cell Line
Down-Regulation
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Humans
Mutation
Nuclear Proteins--genetics
Phosphoprotein Phosphatases
Phosphorylation
Proto-Oncogene Proteins c-akt--metabolism
RNA, Small Interfering--genetics
Ubiquitination
beta-Transducin Repeat-Containing Proteins--genetics