Tranilast suppresses prostate cancer growth and osteoclast differentiation in vivo and in vitro. [electronic resource]
Producer: 20100315Description: 229-38 p. digitalISSN:- 1097-0045
- Animals
- Apoptosis -- drug effects
- Blotting, Western
- Bone Marrow Cells -- cytology
- Bone Neoplasms -- drug therapy
- Cell Differentiation -- drug effects
- Cell Proliferation -- drug effects
- Cells, Cultured
- Dose-Response Relationship, Drug
- Down-Regulation
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Humans
- Male
- Necrosis
- Neoplasm Invasiveness -- pathology
- Neoplasm Transplantation
- Osteoclasts -- cytology
- Phosphorylation -- drug effects
- Prostatic Neoplasms -- pathology
- Proto-Oncogene Proteins c-akt -- metabolism
- Rats
- Rats, Inbred F344
- Skull
- Up-Regulation
- ortho-Aminobenzoates -- administration & dosage
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Publication Type: Journal Article
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