Tranilast suppresses prostate cancer growth and osteoclast differentiation in vivo and in vitro.

Sato, Shinya

Tranilast suppresses prostate cancer growth and osteoclast differentiation in vivo and in vitro. [electronic resource] - The Prostate Feb 2010 - 229-38 p. digital

Publication Type: Journal Article

1097-0045

10.1002/pros.21056 doi


Animals
Apoptosis--drug effects
Blotting, Western
Bone Marrow Cells--cytology
Bone Neoplasms--drug therapy
Cell Differentiation--drug effects
Cell Proliferation--drug effects
Cells, Cultured
Dose-Response Relationship, Drug
Down-Regulation
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Humans
Male
Necrosis
Neoplasm Invasiveness--pathology
Neoplasm Transplantation
Osteoclasts--cytology
Phosphorylation--drug effects
Prostatic Neoplasms--pathology
Proto-Oncogene Proteins c-akt--metabolism
Rats
Rats, Inbred F344
Skull
Up-Regulation
ortho-Aminobenzoates--administration & dosage